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"Coastal Flood Warning" ...Coastal Flood Warning remains in effect from 7 PM to 11 PM EST this evening... * locations...low lying areas along western Long Island Sound. * Tidal departures...3 to 4 ft above astronomical tides in the evening. * Timing...minor to moderate coastal flooding around the times of astronomical high tide...between 7 PM and 11 PM. Minor coastal flooding is possible with the Tuesday morning high tide cycle. * Coastal flood impacts...flooding of vulnerable Waterfront and shoreline roads and adjacent properties due to height of storm tide and wave action. Inundation of 1 to 2 ft in the lowest lying spots. Road closures may be needed. Isolated structural damage may be observed along the immediate shoreline. * Shoreline impacts...elevated water levels in combination with 3 to 5 ft of surf are expected to cause beach erosion and splashover along the shoreline this evening. Precautionary/preparedness actions... A coastal Flood Warning means that flooding is expected or occurring. Coastal residents in the warned area should be alert for rising water...and take appropriate action to protect life and property. ...Western l.I. Sound water levels for this evening... Coastal............time of......forecast total......flood..... Location...........high Tide.....Water level........category.. ...................................(Mllw/mhhw)................ Kings Point NY.......859 PM.....9.9-10.5/2.2-2.7.....Min-mod.. Stamford CT..........821 PM......9.4-9.9/1.6-2.1.....Minor.... Glen Cove NY.........900 PM.....9.6-10.1/2.1-2.7.....Min-mod.. , "High Wind Warning" ...High Wind Warning now in effect until 6 am EST Tuesday... * winds...northeast 30 to 40 mph with gusts up to 60 mph. Gusts 65 to 70 mph possible over Twin Forks of Long Island. * Timing...the strongest winds are expected tonight. * High wind impacts...damaging winds will blow down trees and power lines. Numerous power outages are expected. Travel will be difficult...especially for high profile vehicles and on elevated roadway and bridges. Precautionary/preparedness actions... A High Wind Warning means a hazardous high wind event is expected or occurring. Sustained wind speeds of at least 40 mph or gusts of 58 mph or more can lead to property damage. , "Storm Warning" ...Storm Warning remains in effect until 1 am EST Tuesday... * winds and seas...northeast winds 25 to 30 kt with gusts up to 50 kt. Seas 5 to 9 feet. Precautionary/preparedness actions... A Storm Warning means sustained winds or frequent gusts of 48 to 63 kt are expected or occurring. Recreational boaters should remain in port...or take shelter until winds and waves subside. Commercial vessels should prepare for very strong winds and dangerous sea conditions...and consider remaining in port or taking shelter in port until winds and waves subside. -- Monday Jan.23 17,07:48 PM

Of Balding Mice and Men

Researchers have discovered a lipid which may be the direct cause of hair loss for most balding men.

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Hair loss has long been a bane for the appearance-conscience men of the world. Everything from miracle creams to toupees to hair transplants has been tried to hide or undo this scourge of the scalp, and with 80% of men seeing some sign of male pattern baldness by age 70 it’s no wonder so many industries have sprouted up to remedy the lack of sprouting hair. While it is known that hair follicles in bald skin produce what is essentially short, microscopic hair, science has yet to discover how to restore that hair to its original length and thickness. Though there is no true cure for the problem, new investigations show some promise in generating one.

Following up on a study performed in 2011, researchers from the Perelman School of Medicine at the University of Pennsylvania have discovered a possible cause for hair loss. The journey started with an examination of balding scalps which revealed that hair-growing stem cells were as prevalent in bald skin as in skin that still grew hair. Because the cells were, however inactive, still present, the hope that they could be reactivated arose and focus shifted toward finding what exactly caused them to become dormant in the first place.

An abundance of a lipid known as Prostaglandin D2 was eventually found, exceeding the levels of normal skin threefold. When large quantities of the lipid were added to cultured hair follicles it was seen to cause a shortening and inhibition of hair growth. With further probing, it may be possible to undo the over-accumulation of Prostaglandin D2 and reignite the growth of hair in already bare skin or prevent it from stopping in the first place.

An earlier study of lab mice yielded similar results, and may help in developing treatments for humans as well.  The mice in this study, like bald men, still had a normal number of stem cells which contained the genetic materials needed to grow hair. By activating dormant molecular pathways in these cells, researchers found they could create new, healthy hair follicles. If the analogous paths in humans can be similarly activated, this could be coupled with a treatment for the removal of Prostaglandin D2 to grow new hair in men.

 

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